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wb403WB403 (WB-403) is a novel and potent TGR5 activator with antidiabetic effects. It can improve glucose tolerance and decrease fasting blood glucose, postprandial blood glucose and HbA1cEffects of WB403 treatment in dbdb mice. (A, B) G and PBG measured every week during the 4-week treatment period. (C, D) Serum levels of HbA1c, measured at the